China (Mainland)
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- Product Details
Keywords
- allantoin
- 97-59-6
- 5-ureidohydantoin
Quick Details
- ProName: glyoxyldiureide
- CasNo: 97-59-6
- Molecular Formula: C4H6N4O3
- Appearance: White crystalline powder, odorless and...
- Application: Widely used in all kinds of skin ulcer...
- DeliveryTime: 7-10days
- PackAge: 25kg/paper barrel
- Port: Shanghai/Taicang
- ProductionCapacity: 3000 Metric Ton/Year
- Purity: ≥98.5%
- Storage: stored in dark, cool, dry place in wel...
- Transportation: shipping
- LimitNum: 1 Metric Ton
- Related Substances: ≥98.5%
- Residue on Ignition: ≤0.5%
- Heavy Metal: ≤0.001%
- Valid Period: 24 months
Superiority
High-purity Allantoin is a kind of white crystal without poison, flavor, irritation and anaphylaxis, dissolving in hot water, hot alcohol and aqueous sodium hydroxide and slightly dissolving in cold water and alcohol, dissolving in nether chloroform nor other organic solvents. The saturated aqueous solution (0.6%) is slightly acidic and its PH is 5.5. The allantion in non-aqueous solvent and dry in the air is stable.
Our allantoin is high purity.
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Details
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Allantoin is present in botanical extracts of the comfrey plant and in the urine of most mammals. Chemically synthesized bulk allantoin, which is chemically equivalent to natural allantoin, is safe, non-toxic, compatible with cosmetic raw materials and meets CTFA and JSCI requirements. Over 10,000 patents reference allantoin.
Cosmetics and toiletries
Manufacturers cite several beneficial effects for allantoin as an active ingredient in over-the-counter cosmetics, including: a moisturizing and keratolytic effect, increasing the water content of the extracellular matrix and enhancing the desquamation of upper layers of dead skin cells, increasing the smoothness of the skin; promoting cell proliferation and wound healing; and a soothing, anti-irritant, and skin protectant effect by forming complexes with irritant and sensitizing agents.
A animal study in 2010 found that based on the results from histological analyses, a soft lotion with 5% allantoin ameliorates the wound healing process, by modulating the inflammatory response. The study also suggests that quantitative analysis lends support to the idea that allantoin also promotes fibroblast proliferation and synthesis of the extra cellular matrix. [6]
A study published in 2009 reported the treatment of pruritus in mild-to-moderate a topic dermatitis with a topical non-steroidal agent containing allantoin.[7]
Pharmaceuticals
It is frequently present in toothpaste, mouthwash, and other oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions, various cosmetic lotions and creams, and other cosmetic and pharmaceutical products.
Biomarker of oxidative stress
Since uric acid is the end product of the purine metabolism in humans, only non-enzymatic processes with reactive oxygen species will give rise to allantoin, which is thus a suitable biomarker to measure oxidative stress in chronic illnesses and senescence. |